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| Injection de Lactate de Ciprofloxacine (Injection de Lactate de Ciprofloxacine) |
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Description:
The product is colorless or almost colorless pellucid liquid.
Pharmacology and toxicity:
Broad spectrum aerobicidal quinolone antibiotic. In vitro ciprofloxacin lactate can resist all of the G- Bacteria effectively. It also has effect on the resistance of G+ Bacteria. But it has lower sensibility for the anaerobic bacteria. As a kind of bactericidal agent, ciprofloxacin can inhibit DNA screw enzyme, preventing them from the metabolism, and lead to bacteria dead.
Pharmacokinetics:
After administering by intravenous drip 0.2g or 0.4g, the plasma peak concentration (Cmax) is 2.1μg/ml and 4.6μg/ml respectively. The medicine distributes widely to all kinds of tissues and body liquids (including cerebrospinal fluid), the concentration in the tissues usually exceed the concentration in the plasma. The binding rate with protein is about 20%~40%. 50%~70% of Ciprofloxacin Lactate is excreted, about 15% of the medicine is excreted as metabolism and a large amount of the medicine is excreted in bile and dejection.
Disease treated:
Used for the treatment of:
1. Urinary tract infections
2. Respiratory tract infections
3. Gastrointestinal infections
4. Typhia
5. Bone & joint infections
6. Skin & soft Tissue infections
7. General infection including blood poisoning
Administration and dosage by drip phleboclysis. Dose for the adult is 0.2g every day, with interval 12hours, administration time not less than 30minutes. For the acute infection and infection caused by some bacteria, the dose can be increased to 0.8g/day, two times every day.
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