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| Artemether Lumefantrine 20mg+ 120mg Tablet (Artemether Lumefantrine 20mg+ 120mg Tablet) |
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Qualitative and quantitative composition
One tablet contains 20 mg artemether and 120 mg lumefantrine.
For a full list of excipients, see section 6.1.
Pharmaceutical form
Tablet.
Light yellow, round tablet with “NC” debossed on one side and “CG” on the other.
Clinical particulars
Therapeutic indications
Riamet is indicated for the treatment of acute uncomplicated Plasmodium falciparum malaria in adult, children and infants of 5 kg and above.
Consideration should be given to official guidance regarding the appropriate use of antimalarial agents.
Posology and method of administration
Tablets for oral administration.
To increase absorption, Riamet should be taken with food or a milky drink (see section 5.2). If patients are unable to tolerate food, Riamet should be administered, but the systemic exposure may be reduced. Patients who vomit within 1 hour of taking the medication should repeat the dose.
For administration to small children and infants, the tablet/s may be crushed.
Adults and children weighing 35 kg and above
For patients 12 years of age and above and 35 kg body weight and above, a course of treatment comprises six doses of four tablets i.e. total of 24 tablets, given over a period of 60 hours as follows: the first dose of four tablets, given at the time of initial diagnosis, should be followed by five further doses of four tablets given at 8, 24, 36, 48 and 60 hours thereafter.
Children and infants weighing 5 kg to less than 35 kg
A six-dose regimen is recommended with 1 to 3 tablets per dose, depending on bodyweight:
5 to less than 15 kg bodyweight: the first dose of one tablet, given at the time of initial diagnosis, should be followed by five further doses of one tablet given at 8, 24, 36, 48 and 60 hours thereafter.
15 to less than 25 kg bodyweight: the first dose of two tablets, given at the time of initial diagnosis, should be followed by five further doses of two tablets given at 8, 24, 36, 48 and 60 hours thereafter.
25 to less than 35 kg bodyweight: the first dose of three tablets, given at the time of initial diagnosis, should be followed by five further doses of three tablets given at 8, 24, 36, 48 and 60 hours thereafter. |
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